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Published on February 9, 2022

A review of the strongest evidence available identifies differing optimal vitamin D levels needed to help prevent diseases known as major causes of death

Key Points

  • A new review by Grant et al. has defined optimal vitamin D levels necessary to help prevent certain diseases known to be major causes of death, based on a review of the strongest evidence published to date
  • Optimal vitamin D levels needed for each outcome ranged from 25 ng/ml to 60 ng/ml – all of which were above the 20 ng/ml vitamin level recommended by the Institute of Medicine
  • Each system within the body has its own requirement for vitamin D in order to function optimally – measuring the vitamin D level is the only way to tell if you are getting enough vitamin D for your specific health concerns

Dr. William Grant is a GrassrootsHealth scientist panel member who has published many papers on vitamin D which been cited over 20,000 times, according to Scholar.Google.com.  He is listed as a top author for both Vitamin D and Vitamin D Deficiency, and has received the “World Expert” title for sunlight.

A new review by Grant et al. has defined optimal vitamin D levels necessary to help prevent certain diseases known to be major causes of death, based on a review of the strongest evidence published to date. Diseases identified as those with the highest mortality rates included cardiovascular disease, hypertension, cancer, type 2 diabetes, Alzheimer’s Disease, and COVID-19.

Vitamin D Levels Required to Achieve Various Health Results

The findings, which are illustrated in the graph below, showed that optimal vitamin D levels needed for each outcome ranged from 25 ng/ml to 60 ng/ml – all of which were above the 20 ng/ml vitamin level recommended by the Institute of Medicine.

Click to Enlarge & Print

As the authors state, based on the evidence, “…given the multiple indications of significant health benefits from raising serum 25(OH)D concentrations above 30 or 40 ng/mL as well as the near absence of adverse effects, significant improvements in health at the individual and population levels could be achieved.”  These results could be seen simply through achieving and maintaining optimal vitamin D levels!

Different Requirements for Different Systems and Outcomes

The significance of vitamin D on disease prognosis has been demonstrated by thousands of studies, on many different diseases or conditions, including breast cancer, prostate cancer and other cancers, thyroid disease, diabetes, and others. Each system within the body has its own requirement for vitamin D in order to function optimally. For example, while bone health may be optimized with a vitamin D level of at least 20 ng/ml, immune health may not be optimized until a vitamin D level of at least 50 ng/ml has been achieved, and the greatest reduction in breast cancer risk may not be seen until a vitamin D level of at least 60 ng/ml has been reached.

The Disease Incidence Prevention (DIP) Chart was one of the first graphics created by GrassrootsHealth, and it remains the most popular. It displays the reduction in risk of several diseases based on varying vitamin D levels. The DIP chart along with the Grant et al. study are reminders that

“…raising serum 25(OH)D concentrations to optimal concentrations will result in a significant reduction in preventable illness and death.”

Measuring vitamin D status and supplementing to reach optimal levels is a safe, simple, and effective way to improve health and help prevent disease – start by finding out your level today!

Are You Getting Enough Vitamin D for Your Health Concerns?

Having and maintaining healthy vitamin D levels and other nutrient levels can help improve your health now and for your future. Choose which additional nutrients to measure, such as your omega-3s and essential minerals including magnesium and zinc, by creating your custom home test kit today. Take steps to improve the status of each of these measurements to benefit your overall health. You can also track your own intakes, symptoms and results to see what works best for YOU.

Enroll and test your levels today, learn what steps to take to improve your status of vitamin D (see below) and other nutrients and blood markers, and take action! By enrolling in the GrassrootsHealth projects, you are not only contributing valuable information to everyone, you are also gaining knowledge about how you could improve your own health through measuring and tracking your nutrient status, and educating yourself on how to improve it.

How Can You Use this Information for YOUR Health?

Having and maintaining healthy vitamin D and other nutrient levels can help improve your health now and for your future. Measuring is the only way to make sure you are getting enough!

STEP 1 Order your at-home blood spot test kit to measure vitamin D and other nutrients of concern to you, such as omega-3s, magnesium, essential and toxic elements (zinc, copper, selenium, lead, cadmium, mercury); include hsCRP as a marker of inflammation or HbA1c for blood sugar health

STEP 2 Answer the online questionnaire as part of the GrassrootsHealth study

STEP 3 Using our educational materials and tools (such as our dose calculators), assess your results to determine if you are in your desired target range or if actions should be taken to get there

STEP 4 After 3-6 months of implementing your changes, re-test to see if you have achieved your target level(s)

Enroll in D*action and Build Your Custom Test Kit!