Published on April 14, 2021

The Australian Government has officially added omega-3 fatty acid supplementation to their list of recommendations for pregnant women

Omega-3 fatty acids are essential to a healthy pregnancy and baby, and are known to be important for many aspects of health. This includes being extremely important for vision and normal brain growth and development during pregnancy and infancy. Many studies have shown a relationship between omega-3 intake or status during pregnancy and outcomes such as infant immunity, time of gestation or preterm birth, birth weight, and even the incidence of postpartum depression.

Now, the Australian Government, Department of Health has officially made the recommendation for daily supplementation with omega-3 long-chain polyunsaturated fatty acids (800 mg docosahexaenoic acid [DHA] and 100 mg eicosapentaenoic acid [EPA]) during pregnancy, with the emphasis that they may reduce the risk of preterm birth among women who are low in omega-3s. This recommendation is included in the list of other lifestyle factors that contribute to the health and wellbeing of a woman and her baby during pregnancy. Other recommendations include eating a healthy diet, getting regular physical activity, not smoking, and avoiding alcohol, as well ensuring adequate folic acid, iron, calcium, and iodine intake, such as by taking a prenatal multivitamin.

Preterm Birth Risk Reduced with Omega-3s

A meta-analysis by Kar et al. looked at the relationship between omega-3 fatty acid supplementation and the risk of preterm birth by combining data from 9 randomized controlled trials, from a total of 5980 women. Specific outcomes measured were the effect of omega-3 fatty acid supplementation on the risk of preterm (<37 weeks gestation) and early preterm (<34 weeks gestation) birth. All women included in the studies had singleton pregnancies and were not on any other treatment for the prevention of preterm delivery. Omega-3 fatty acid intake was identified to include either EPA, DHA or both, with doses ranging from 133 mg per day to 3000 mg per day. Only 1 of the 9 studies gave less than 400 mg per day, and 7 of the 9 studies began supplementation before the end of the second trimester (24 weeks of gestation).

Six of the studies included early preterm birth as an outcome, and found that omega-3 intake was associated with a 58% reduced risk of early preterm delivery (p=0.0002). Overall, a 17% decreased risk of any preterm birth was seen among women who supplemented with omega-3s (p=0.03).

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The review also found that, among the women who supplemented with omega-3s, there was a significant increase in the mean gestational age by nearly two weeks (p=0.01) and a significant increase in the mean birth weight by 122 g (p=0.001).

A Low Omega-3 Index Is a Risk Factor for Postpartum Depression

In a study by Markhus et al., researchers measured Omega-3 Index levels (the same measurement provided in D*action+Omega-3, which measures the amount of EPA and DHA in red blood cell membranes) and found a direct correlation between Omega-3 Index levels and postpartum depression. The study was done in Norway, examining women from a single community, whose Omega-3 Index levels were measured at 28 weeks gestation. The women were assessed for postpartum depression three months after delivery using the Edinburgh Postnatal Depression Scale (EPDS) with scores ranging from 0-30. A value of greater than or equal to ten usually equates to having postpartum depression.

Overall, only 6.9% of the women in the study had EPDS values of 10 or higher – but as can be seen in the chart below, the higher the Omega-3 Index, the lower the EPDS score. This paper describes a ‘bend’ in the curve at an Omega-3 Index around 5%, in others words, that is the point you want to be above to reduce the risk of postpartum depression. An Omega-3 Index of almost 8% was associated with an even greater risk reduction, and has also been associated with the greatest improvement in cardiovascular health, cognitive health, and healthy aging.

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Omega-3 Supplementation in Pregnancy May Boost Babies Immunity

Granot et al. investigated whether DHA supplementation during pregnancy and lactation affected immune cell numbers and function in babies breastfed up to 4 months of age. The study found that the number of T cell subsets (discussed in a previous post) were affected by DHA supplements. Women who were supplemented with 400 mg DHA per day from the first trimester until up to 4 months after birth had babies who experienced lower levels of inflammation and higher numbers of immune cells known for fighting off viral infections. Overall, this research suggests that DHA supplementation specifically during pregnancy and breast feeding may result in an improved immune response of the infant.

How Much Omega-3s Do You Need?

An analysis of GrassrootsHealth data found that approximately 1,300 mg/day of EPA+DHA was needed for 50% of the population and 1,900 mg/day was needed for 90% of the population to achieve and Omega-3 Index of 8%. It is important to point out that, similar to the large variability seen with vitamin D dose response to intake, these intake amounts are averages and there is a large amount of variability in the omega-3 status for different people with the same intake amount. For example, our initial analysis showed that the range of response with 1000 mg of EPA+DHA per day was 5.7% to 10.2%. Therefore, we recommend that individuals measure their Omega-3 Index and determine a personalized dose.

Once results are received, consider your next steps for adjusting the Omega-3 Index, such as how to choose between the different types of omega-3 sources, how to evaluate and choose an omega-3 supplement, and how to achieve a desired Omega-3 Index using an estimated dose of EPA and DHA as determined by our Omega-3 calculator. Taking simple dietary steps to increase consumption of foods rich in EPA and DHA can also help increase your Omega-3 Index.

Vitamin D is also Essential for a Healthy Mom and Baby

Several studies have shown that achieving a vitamin D level of 40 ng/ml (100 nmol/L) during pregnancy is related to decreased risk of preterm birth and other complications in pregnancy and early childhood. In 2015, GrassrootsHealth partnered with the Medical University of South Carolina (MUSC) to initiate a new standard of care to screen all pregnant women at their hospitals for vitamin D levels and provide them with supplements to help get their levels up to at least 40 ng/ml. Overall, women who got their vitamin D level to at least 40 ng/ml (100 nmol/L) by the time of delivery had a 62% lower risk of preterm birth compared to women with levels under 20 ng/ml (50 nmol/L).

Healthy Omega-3 and Vitamin D Levels are Necessary for All Stages of Life – What are Yours?

By joining the GrassrootsHealth projects, you are not only contributing valuable information to our study, but you are also gaining knowledge about how you could improve your own health through measuring and tracking your nutrient status, and educating yourself on how to improve it. Do you know what your status of vitamin D, omega-3s, and other essential nutrients is? Could your levels be improved? Test now to find out!

We now have a NEW GIFTING SERVICE that allows you to quickly send ‘Gift Cards’ to friends, family and coworkers who you consider might need immediate access to testing, and to Claim the Joy of Your Health TODAY. Give the gift today!

What does the Research Say about Vitamin D & COVID-19?

It’s TIME to start saving lives! If you can help PREVENT the majority of the death, it’s time! What’s it costing you/us not to take action NOW?

There is much published research that supports a clear link between vitamin D and COVID-19 showing that higher vitamin D levels are related to:

a decreased risk of testing positive for COVID-19

increased viral SARS-CoV-2 RNA clearance

better clinical outcomes among patients with COVID-19

less severe COVID-19 disease

decreased risk of death due to COVID-19

Be sure to educate yourself on the benefits and importance of vitamin D for immune health, and take steps to ensure you and your loved ones are getting enough.

You can review all of the COVID-19 and immune health information we have shared on this page.

What Does it Take YOU to Get Your D to 40 ng/ml (100 nmol/L)?

Did you know your health could be greatly affected by making sure you have a vitamin D level of at least 40 ng/ml (100 nmol/L)? Help us help you.

STEP 1 - Do you know what your vitamin D level is? If not, be sure to test today to find out.

STEP 2 – Determine your target level. Are you at your target level? Experts recommend a level of at least 40-60 ng/ml (100-150 nmol/L).

STEP 3 – Need to boost your level? Use the D*calculator to see how much vitamin D it may take to reach your target. Opt for the Loading Dose for a quicker boost.

STEP 4 – Optimize how your body absorbs and utilizes vitamin D with co-nutrients and these simple steps.

STEP 5 – Re-Test! This is an important step to make sure you have reached your target level, and to ensure you are not taking too much! Re-testing after 3-4 months is recommended.

STEP 6 – Adjust, Repeat…

Give your immune system the nutrients it needs to support a healthy you and protect yourself from unnecessary diseases, especially COVID-19.


The first Randomized Controlled Trial on vitamin D and COVID-19 has shown a 96% lower risk of ICU admission for those receiving vitamin D (as 25(OH)D to quickly boost vitamin D blood levels) along with the standard treatment, compared to those receiving standard treatment alone.

These results support many previous observational studies showing a relationship between vitamin D levels and intake and COVID-19 severity.

Review the Latest Nutrient Research for COVID-19

GrassrootsHealth Nutrient Research Institute has launched the new Immune Boost project with the use of our myData-myAnswers nutrient health system that nearly 15,000 people are already using for their health. Specific markers that influence immune health are suggested for testing as part of this project including:

  • Vitamin D
  • Omega-3 Index
  • Essential elements magnesium, selenium, and zinc
  • hsCRP

Our goal is to demonstrate how one can use the Nutrient Research Model established by Dr. Robert Heaney to show the effect of vitamin D serum levels of at least 40 ng/ml (100 nmol/L) on risk reduction for all ethnicities in the population. Status and intake of other nutrients will also be analyzed for any type of relationship to immune status and symptom severity. Join the project today!

Please let us know if you're interested in helping sponsor this project.

CLICK HERE for updates and new information about the project.

Through GrassrootsHealth Nutrient Research Institute, you can also test your essential elements magnesium, copper, zinc and selenium, toxins such as lead, mercury and cadmium, as well as your omega-3 levels, inflammation levels and thyroid stimulating hormone (TSH) level. Find out your levels today! Log on to the test selection page (click the link below) to get your tests and see for yourself if your levels can be improved.

Make sure you track your results before and after, about every 6 months!

Click Here to Access the Test Page

How can I track my nutrient intake and levels over time?

To help you track your supplement use and nutrient levels, GrassrootsHealth has created the Personal Health Nutrient Decision System called

For each specific supplement, you can track what days you take it, how much, and many other details.  This will help you know your true supplemental intake and what patterns of use work for you to reach and maintain optimum nutrient levels. Check it out today!